Description

1-[2-(Trifluoromethyl)Benzyl]Hydrazine Dihydrochloride is a high-purity, organofluorine building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, where the hydrazine moiety and fluorine atoms contribute to enhanced efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced polymers and functional materials with specific thermal or chemical resistance properties.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways in academic and industrial research settings.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Benzyl]Hydrazine Dihydrochloride
CAS No.	1349717-46-9
Molecular Formula	C8H10Cl2F3N2
Molecular Weight	263.08 g/mol
Synonyms	2-(Trifluoromethyl)benzylhydrazine dihydrochloride; (2-(Trifluoromethyl)phenyl)methanamine, N-amino-, dihydrochloride; 1-[(2-Trifluoromethyl)phenyl]methylhydrazine dihydrochloride; α-(Trifluoromethyl)benzylhydrazine dihydrochloride; 1-[2-(Trifluoromethyl)benzyl]hydrazine hydrochloride (1:2); Hydrazine, [2-(trifluoromethyl)phenyl]methyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethyl)Benzyl]Hydrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.