Description

n-(2,4,6-Trifluorobenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its dihydrochloride salt form, which enhances stability and handling properties. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new drug candidates.

Application

• Critical building block in the research and synthesis of novel pharmaceutical compounds.
• Key intermediate for the development of potential central nervous system (CNS) drug candidates.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Essential raw material in the production scale-up of active pharmaceutical ingredients (APIs) under GMP conditions.
• Employed in the synthesis of compounds for preclinical and clinical research.
• Valuable intermediate for creating libraries of compounds in high-throughput screening.

Basic Information

Product Name	n-(2,4,6-Trifluorobenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1349717-05-0
Molecular Formula	C12H15Cl2F3N2
Molecular Weight	315.16 g/mol
Synonyms	4-Amino-1-[(2,4,6-trifluorophenyl)methyl]piperidine dihydrochloride; 1-[(2,4,6-Trifluorophenyl)methyl]piperidin-4-amine dihydrochloride; Piperidin-4-amine, N-(2,4,6-trifluorobenzyl)-, dihydrochloride; (2,4,6-Trifluorobenzyl)(4-aminopiperidin-1-yl)methanone dihydrochloride (common misnomer); 4-Amino-1-(2,4,6-trifluorobenzyl)piperidine dihydrochloride; TFBP-4-Amine Dihydrochloride; 1349717-05-0
EINECS	Contact for details

Quality Control

Our n-(2,4,6-Trifluorobenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.