Description

4-Bromo-5-Chloro-2-Methylbenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, multi-functional scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a derivatization agent or a linker molecule in the design of chemical probes and bioconjugates.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in university and corporate research laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Methylbenzoic Acid
CAS No.	1349716-38-6
Molecular Formula	C8H6BrClO2
Molecular Weight	249.49 g/mol
Synonyms	2-Methyl-4-bromo-5-chlorobenzoic Acid; 4-Bromo-5-chloro-o-toluic Acid; Benzoic acid, 4-bromo-5-chloro-2-methyl-; 5-Chloro-4-bromo-2-methylbenzoic Acid; 4-Bromo-5-chloro-2-methyl-benzoic acid; 2-Methyl-4-bromo-5-chlorobenzoic acid; 4-Br-5-Cl-2-Me-BA
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.