Description

(1R*,4R*)-N1-(Oxetan-3-Yl)Cyclohexane-1,4-Diamine is a chiral diamine building block featuring a cyclohexane backbone substituted with an oxetane ring. This compound is valued for its rigid, three-dimensional structure and dual amine functionality, making it a versatile intermediate in sophisticated organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and antiviral therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific stereochemistry for enhanced activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Science: Incorporated into polymers and resins to modify thermal stability, rigidity, and chemical resistance.
• Peptidomimetics & Bio-conjugation: The amine groups facilitate its use in constructing peptide analogs and for bioconjugation chemistry in probe development.
• Academic & Contract Research: A valuable tool for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	(1R*,4R*)-N1-(Oxetan-3-Yl)Cyclohexane-1,4-Diamine
CAS No.	1349709-08-5
Molecular Formula	C11H20N2O
Molecular Weight	196.29 g/mol
Synonyms	(1R,4R)-N1-(Oxetan-3-yl)cyclohexane-1,4-diamine; (1R,4R)-N-(Oxetan-3-yl)cyclohexane-1,4-diamine; rel-(1R,4R)-N1-(Oxetan-3-yl)cyclohexane-1,4-diamine; (1R,4R)-1-Amino-4-[(oxetan-3-yl)amino]cyclohexane; 3-[[(1R,4R)-4-Aminocyclohexyl]amino]oxetane; Oxetane-3-yl-(1R,4R)-cyclohexane-1,4-diamine; CAS 1349709-08-5
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-N1-(Oxetan-3-Yl)Cyclohexane-1,4-Diamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.