Description

(R)-1-(3-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride CAS NO 1349702-39-1 is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for creating enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing novel therapeutics, especially in the areas of central nervous system (CNS) and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Asymmetric Synthesis: Serves as a chiral amine precursor or catalyst ligand in stereoselective chemical transformations.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Bioconjugation & Probe Development: Useful for modifying biomolecules or creating chemical probes for biological target identification.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacology studies.

Basic Information

Product Name	(R)-1-(3-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride
CAS No.	1349702-39-1
Molecular Formula	C11H16BrN2·2HCl
Molecular Weight	352.09 g/mol (for dihydrochloride salt)
Synonyms	(R)-1-[(3-Bromophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (3R)-1-[(3-Bromophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (R)-1-(3-Bromobenzyl)pyrrolidin-3-amine hydrochloride (1:2); (R)-3-Amino-1-(3-bromobenzyl)pyrrolidine dihydrochloride; 1-(3-Bromobenzyl)-3-aminopyrrolidine (R)-enantiomer dihydrochloride; (R)-1-(3-Bromobenzyl)-3-aminopyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and related substances are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.