Description

(S)-1-Methyl-3-(Piperidin-3-Yl)Urea Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric research. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules for preclinical and clinical studies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in chiral pool synthesis due to its defined (S)-configuration at the stereogenic center.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and enzyme interactions.

Basic Information

Product Name	(S)-1-Methyl-3-(Piperidin-3-Yl)Urea Hydrochloride
CAS No.	1349700-05-5
Molecular Formula	C8H18ClN3O
Molecular Weight	207.70 g/mol
Synonyms	(S)-1-Methyl-3-(3-piperidyl)urea hydrochloride; (3S)-1-Methyl-3-(3-piperidinyl)urea monohydrochloride; Urea, N-methyl-N-[(3S)-3-piperidinyl]-, monohydrochloride; (S)-N-Methyl-N'-(piperidin-3-yl)urea hydrochloride; (S)-3-(3-Methylureido)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-Methyl-3-(Piperidin-3-Yl)Urea Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.