Description

(R)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and functionalized piperidine core, which is crucial for the synthesis of targeted bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring specific enantiomeric control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Utilized in the construction of complex molecules where the (R)-configured piperidine-3-yl moiety is required for biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Used in the synthesis of compounds for pharmacological profiling, toxicology studies, and early-stage formulation development.
• Chemical Biology Probes: Acts as a component in the design of molecular probes for studying enzyme function and receptor interactions.

Basic Information

Product Name	(R)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride
CAS No.	1349699-86-0
Molecular Formula	C8H17N3O • HCl
Molecular Weight	207.70 g/mol
Synonyms	(R)-1-(3-Piperidinyl)-3,3-dimethylurea hydrochloride; (R)-3,3-Dimethyl-1-(3-piperidinyl)urea hydrochloride; (R)-N-(3-Piperidinyl)-N',N'-dimethylurea hydrochloride; Urea, N-(3-piperidinyl)-N',N'-dimethyl-, (R)-, hydrochloride; (R)-3,3-Dimethyl-1-(piperidin-3-yl)urea HCl; (R)-1-(Piperidin-3-yl)-3,3-dimethylurea hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, and NMR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.