Description

(R)-n-(Oxetan-3-Yl)Pyrrolidin-3-Amine is a high-purity chiral amine building block of significant interest in advanced pharmaceutical synthesis. This compound matters as a key intermediate for constructing complex molecules with specific three-dimensional configurations, which are critical for developing targeted therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs), particularly in areas like oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel drug candidates, especially for kinase inhibitors and other targeted therapies.
• Asymmetric Synthesis: Used as a building block or chiral auxiliary in catalytic asymmetric reactions to introduce stereochemical complexity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Process Chemistry Development: Serves as a starting material for scaling up the synthesis of advanced intermediates under Good Manufacturing Practice (GMP) conditions.
• Ligand and Catalyst Preparation: Potential precursor for the synthesis of novel ligands used in homogeneous catalysis.

Basic Information

Product Name	(R)-n-(Oxetan-3-Yl)Pyrrolidin-3-Amine
CAS No.	1349699-80-4
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-3-(Oxetan-3-ylamino)pyrrolidine; (3R)-N-(Oxetan-3-yl)pyrrolidin-3-amine; (R)-N-(Oxetan-3-yl)-3-pyrrolidinamine; (R)-3-(Oxetan-3-ylamino)pyrrolidine; Pyrrolidine, 3-[(3R)-3-oxetanylamino]-; (R)-N-(Oxetanyl-3-yl)pyrrolidin-3-amine; (R)-3-(Oxetan-3-ylamino)azacyclopentane
EINECS	Contact for details

Quality Control

Our (R)-n-(Oxetan-3-Yl)Pyrrolidin-3-Amine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data including chiral purity confirmation. A Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profile is supplied with every batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.