Description

1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Amine is a high-value, synthetically versatile spirocyclic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique diazaspiro[3.3]heptane core is of significant interest for constructing conformationally constrained molecules with enhanced pharmacological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Scaffold: Used to introduce the rigid, three-dimensional diazaspiro[3.3]heptane structure into compound libraries for structure-activity relationship (SAR) studies.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or insecticides that benefit from its unique molecular geometry.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating tool compounds to study biological pathways and protein function.
• Ligand Development: Potential use in constructing sophisticated ligands for catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized intermediate.

Basic Information

Product Name	1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Amine
CAS No.	1349199-73-0
Molecular Formula	C20H25N3O2S
Molecular Weight	371.50 g/mol
Synonyms	1-Benzyl-6-(4-methylphenyl)sulfonyl-1,6-diazaspiro[3.3]heptan-3-amine; 3-Amino-1-benzyl-6-tosyl-1,6-diazaspiro[3.3]heptane; 1,6-Diazaspiro[3.3]heptan-3-amine, 1-benzyl-6-[(4-methylphenyl)sulfonyl]-; Bn-Ts-DAH-amine; 1-Benzyl-6-(p-toluenesulfonyl)-1,6-diazaspiro[3.3]heptan-3-amine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.