Description

1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-One is a high-value, synthetically versatile spirocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique diazaspiro[3.3]heptane core is a privileged scaffold in medicinal chemistry, enabling the development of novel molecular architectures. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries focused on creating new active ingredients with improved properties.

Application

• As a key synthetic intermediate in the research and development of novel pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Utilized in the construction of spirocyclic scaffolds for fragment-based drug discovery and library synthesis.
• Serves as a versatile precursor for the synthesis of complex molecules in agrochemical research for new crop protection agents.
• Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and exploring new chemical space.
• Potential use in the synthesis of specialty chemicals and advanced materials requiring rigid, three-dimensional molecular frameworks.

Basic Information

Product Name	1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-One
CAS No.	1349199-71-8
Molecular Formula	C20H22N2O3S
Molecular Weight	370.47 g/mol
Synonyms	1-Benzyl-6-(4-methylphenyl)sulfonyl-1,6-diazaspiro[3.3]heptan-3-one; 1,6-Diazaspiro[3.3]heptan-3-one, 1-benzyl-6-[(4-methylphenyl)sulfonyl]-; 1-Benzyl-6-(p-toluenesulfonyl)-1,6-diazaspiro[3.3]heptan-3-one; BTDH; Benzyl-Tosyl-Diazaspiroheptanone; Spirocyclic Tosylamine Building Block
EINECS	Contact for details

Quality Control

Our production of 1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.