Description

1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Ol is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiroalkane chemical class. This compound is of significant value for its role as a key building block in the synthesis of novel, small-molecule drug candidates, particularly in therapeutic areas requiring complex molecular architectures. Research and development teams in the pharmaceutical and biotechnology sectors require this precise chemical to accelerate their discovery and process development workflows.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs, especially for central nervous system (CNS) and oncology targets.
• Process Chemistry Development: Serves as a key starting material for optimizing scalable synthetic routes in pilot plant and commercial manufacturing.
• Bioconjugation & Probe Development: The functional groups present make it suitable for developing chemical probes and bioconjugates for biochemical assays.
• Academic & Institutional Research: Utilized in universities and research institutes for studying spirocyclic compound properties and developing new synthetic methodologies.

Basic Information

Product Name	1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Ol
CAS No.	1349199-70-7
Molecular Formula	C20H24N2O3S
Molecular Weight	372.48 g/mol
Synonyms	1-Benzyl-6-(4-methylphenyl)sulfonyl-1,6-diazaspiro[3.3]heptan-3-ol; 1,6-Diazaspiro[3.3]heptan-3-ol, 1-benzyl-6-[(4-methylphenyl)sulfonyl]-; 1-Benzyl-6-tosyl-1,6-diazaspiro[3.3]heptan-3-ol; BTDH; Bn-Tos-Diazaspiroheptanol; Spirocyclic Tosylamine Intermediate; Benzyl-Tosylated Diazaspiroheptanol
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Tosyl-1,6-Diazaspiro[3.3]Heptan-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.