Description

tert-Butyl 3-Amino-1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new drug candidates, especially in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Protease & Kinase Inhibitor Development: The spirocyclic structure is valuable for creating potent and selective enzyme inhibitors.
• CNS Drug Discovery: Serves as a scaffold for compounds targeting neurological disorders.
• Chemical Biology Probes: Utilized in the development of tool compounds for target validation and pathway analysis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	tert-Butyl 3-Amino-1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylate
CAS No.	1349199-65-0
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	6-Boc-3-amino-1-oxa-6-azaspiro[3.3]heptane; tert-Butyl 3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate; 1-Oxa-6-azaspiro[3.3]heptane-6-carboxylic acid, 3-amino-, 1,1-dimethylethyl ester; 3-Amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylic acid tert-butyl ester; Boc-3-Amino-1-oxa-6-azaspiro[3.3]heptane; 1349199-65-0; 3-Amino-6-Boc-1-oxa-6-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-Amino-1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.