Description

6-Tosyl-1-Oxa-6-Azaspiro[3.3]Heptan-3-Ol is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting complex diseases. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring constrained, three-dimensional spirocyclic structures.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore new chemical space and improve the pharmacokinetic properties of drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Agrochemical Synthesis: Employed in the research and development of new generation herbicides or insecticides with novel modes of action.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Academic Research: A valuable reagent for universities and research institutes investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Tosyl-1-Oxa-6-Azaspiro[3.3]Heptan-3-Ol
CAS No.	1349199-64-9
Molecular Formula	C12H15NO4S
Molecular Weight	269.32 g/mol
Synonyms	1-Oxa-6-azaspiro[3.3]heptan-3-ol, 6-(4-methylbenzenesulfonyl)-; 6-(p-Toluenesulfonyl)-1-oxa-6-azaspiro[3.3]heptan-3-ol; 6-Tosyl-1-oxa-6-azaspiro[3.3]heptan-3-ol; 6-(Tosyl)-1-oxa-6-azaspiro[3.3]heptan-3-ol; 1-Oxa-6-azaspiro[3.3]heptan-3-ol, 6-tosyl-; Spiro[3.3]heptane-1,6(2H)-dione derivative
EINECS	Contact for details

Quality Control

Our 6-Tosyl-1-Oxa-6-Azaspiro[3.3]Heptan-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.