Description

6-Boc-1-Oxa-6-Azaspiro[3.3]Heptan-3-One is a high-value, protected heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique spirocyclic scaffold containing both oxygen and nitrogen atoms makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by medicinal chemists and process development scientists in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce conformational constraint and improve pharmacokinetic properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker component for constructing bifunctional molecules in targeted protein degradation platforms.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides and insecticides with novel modes of action.
• Chemical Biology Probes: Used to create tool compounds for studying enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and exploratory research in organic chemistry.

Basic Information

Product Name	6-Boc-1-Oxa-6-Azaspiro[3.3]Heptan-3-One
CAS No.	1349199-61-6
Molecular Formula	C11H17NO4
Molecular Weight	227.26 g/mol
Synonyms	tert-Butyl 3-oxo-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate; 6-(tert-Butoxycarbonyl)-1-oxa-6-azaspiro[3.3]heptan-3-one; 1-Oxa-6-azaspiro[3.3]heptan-3-one, 6-Boc-protected; Boc-1-Oxa-6-Azaspiro[3.3]Heptan-3-One; 6-Boc-1-oxa-6-azaspiro[3.3]heptan-3-one; 6-Boc-Oxa-Azaspiro[3.3]heptanone; Spirocyclic Boc-protected lactone
EINECS	Contact for details

Quality Control

Our 6-Boc-1-Oxa-6-Azaspiro[3.3]Heptan-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs from discovery through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.