Description

cis-4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid is a high-purity, synthetically versatile chiral building block. This compound is valued for its rigid, substituted cyclohexane core, which is critical for modulating the physicochemical properties and biological activity of advanced molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal Materials: Used in the development of advanced display components due to its stable, substituted cyclohexane structure.
• Organic Synthesis & Catalysis: Employed in asymmetric synthesis and as a ligand precursor in catalytic systems for creating complex, stereodefined molecules.
• Material Science Research: Investigated as a monomer or additive for specialty polymers to impart specific thermal or mechanical properties.

Basic Information

Product Name	cis-4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid
CAS No.	1346600-43-8
Molecular Formula	C13H15ClO2
Molecular Weight	238.71 g/mol
Synonyms	4-(4-Chlorophenyl)cyclohexanecarboxylic acid, cis-; cis-4-(p-Chlorophenyl)cyclohexanecarboxylic Acid; (1r,4r)-4-(4-Chlorophenyl)cyclohexane-1-carboxylic acid; 4-(4-Chlorophenyl)cyclohexanecarboxylic acid (cis-); 4-(4-Chlorophenyl)cyclohexanecarboxylic acid; 1346600-43-8; cis-4-(4-Chlorophenyl)-1-cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of cis-4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with exacting purity and chiral purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.