Description

1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(cis-3-Hydroxycyclohexyl)Urea is a sophisticated, high-purity chemical building block designed for advanced research and development. This compound is critical for medicinal chemistry and pharmaceutical development, serving as a key intermediate in the synthesis of novel therapeutic agents. It is primarily utilized by R&D scientists and process chemists in pharmaceutical, biotechnology, and fine chemical industries for creating targeted molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The urea and sulfonyl pharmacophores make it valuable for designing enzyme inhibitors.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and target engagement.
• Peptidomimetic Synthesis: Employed in the construction of complex, non-peptide molecules that mimic peptide structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke APIs and advanced intermediates under cGMP conditions.

Basic Information

Product Name	1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(cis-3-Hydroxycyclohexyl)Urea
CAS No.	1346598-55-7
Molecular Formula	C20H31N3O6S
Molecular Weight	441.54 g/mol
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-N-[2-[4-[[[[(3S,5R)-3-Hydroxy-1-cyclohexyl]amino]carbonyl]amino]sulfonyl]phenyl]ethyl]glycine tert-Butyl Ester; 1-[4-(2-((tert-Butoxycarbonyl)amino)ethyl)phenylsulfonyl]-3-((1r,3r)-3-hydroxycyclohexyl)urea; (cis)-1-(4-(2-((tert-Butoxycarbonyl)amino)ethyl)phenylsulfonyl)-3-(3-hydroxycyclohexyl)urea; Boc-Protected Sulfonylurea Derivative; CAS 1346598-55-7
EINECS	Contact for details

Quality Control

Our 1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(cis-3-Hydroxycyclohexyl)Urea is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.