Description

1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(trans-4-Hydroxycyclohexyl)Urea is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical synthesis. This compound is critical for researchers and manufacturers requiring precise building blocks for complex molecular architectures. It is primarily utilized in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D for targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of enzyme inhibitors.
• Peptidomimetic Synthesis: Integral for creating urea-based peptidomimetics and other bioisosteres in drug design.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial-scale manufacturing of complex molecules.

Basic Information

Product Name	1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(trans-4-Hydroxycyclohexyl)Urea
CAS No.	1346598-40-0
Molecular Formula	C20H31N3O6S
Molecular Weight	441.54 g/mol
Synonyms	1-[4-[2-[(tert-Butoxycarbonyl)amino]ethyl]phenyl]sulfonyl-3-(trans-4-hydroxycyclohexyl)urea; tert-Butyl N-[2-[4-[[[(trans-4-hydroxycyclohexyl)carbamoyl]amino]sulfonyl]phenyl]ethyl]carbamate; (trans)-1-(4-(2-((tert-Butoxycarbonyl)amino)ethyl)phenylsulfonyl)-3-(4-hydroxycyclohexyl)urea; N-[(1,1-Dimethylethoxy)carbonyl]-N'-[4-[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenethyl]glycine Amide Derivative; Boc-AEPhSUrea-trans-4-OH-CHex; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-[4-(2-n-Boc-2-Aminoethylphenyl)Sulfonyl]-3-(trans-4-Hydroxycyclohexyl)Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.