Description

4-(4-Benzyl-1-Piperazinyl)-3-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative featuring a benzylpiperazine moiety, making it a valuable and versatile building block in advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, particularly for creating novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Key pharmaceutical intermediate in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Building block for the development of fluorinated bioactive molecules, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Precursor in medicinal chemistry research for constructing piperazine-containing compounds, a common pharmacophore in many therapeutic agents.
• Used in process chemistry for scale-up and optimization of synthetic routes for complex organic molecules.
• Starting material for agrochemical research, particularly in creating new herbicides or fungicides with improved properties.
• Reference standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	4-(4-Benzyl-1-Piperazinyl)-3-Fluorobenzoic Acid
CAS No.	1346597-48-5
Molecular Formula	C18H19FN2O2
Molecular Weight	314.36 g/mol
Synonyms	3-Fluoro-4-(4-benzylpiperazin-1-yl)benzoic Acid; 4-(4-Benzylpiperazin-1-yl)-3-fluorobenzoic Acid; 4-(4-Benzyl-1-piperazinyl)-3-fluorobenzoic acid; Benzoic acid, 3-fluoro-4-[4-(phenylmethyl)-1-piperazinyl]-; 1346597-48-5; 3-Fluoro-4-(4-benzyl-1-piperazinyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(4-Benzyl-1-Piperazinyl)-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.