Description

4-Chloro-6-[(1,1-Dimethylethyl)Sulfonyl]Quinoline is a high-value, synthetically versatile quinoline derivative featuring a chloro and a tert-butylsulfonyl substituent. This compound is a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active quinoline-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the quinoline core provides specific biological activity.
• Material Science Precursor: Acts as a starting material for creating functionalized organic compounds used in organic light-emitting diodes (OLEDs) or other advanced materials.
• Chemical Synthesis Reagent: Employed in organic synthesis for introducing the chloroquinoline-sulfone moiety into more complex molecular architectures via cross-coupling or substitution reactions.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) focused on heterocyclic chemistry and drug discovery.

Basic Information

Product Name	4-Chloro-6-[(1,1-Dimethylethyl)Sulfonyl]Quinoline
CAS No.	1346549-11-8
Molecular Formula	C₁₃H₁₄ClNO₂S
Molecular Weight	283.77 g/mol
Synonyms	4-Chloro-6-(tert-butylsulfonyl)quinoline; 6-(tert-Butylsulfonyl)-4-chloroquinoline; 4-Chloro-6-(tert-butylsulfonyl)quinoline; 4-Chloro-6-[(1,1-dimethylethyl)sulfonyl]-quinoline; Quinoline, 4-chloro-6-[(1,1-dimethylethyl)sulfonyl]-; 4-Chloro-6-(tert-butylsulphonyl)quinoline; 4-Chloro-6-(tert-butylsulfonyl)chinolin
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-[(1,1-Dimethylethyl)Sulfonyl]Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.