Description

3-(3,4-Dihydro-2H-Pyrano[2,3-B]-Pyridin-6-Yl)Prop-2-Yn-1-Ol is a high-purity, advanced pharmaceutical intermediate featuring a fused pyranopyridine scaffold with a propargylic alcohol functional group. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile reactive sites.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Synthesis: Intermediate in the research and development of new crop protection agents and pesticides.
• Material Science: Potential monomer or precursor for specialized polymers and advanced organic materials.

Basic Information

Item	Details
Product Name	3-(3,4-Dihydro-2H-Pyrano[2,3-B]-Pyridin-6-Yl)Prop-2-Yn-1-Ol
CAS No.	1346447-31-1
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	6-(3-Hydroxy-1-propyn-1-yl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine; 3-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-2-propyn-1-ol; 3-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)prop-2-yn-1-ol; 6-(3-Hydroxyprop-1-yn-1-yl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine; Pyrano[2,3-b]pyridine-6-propargyl alcohol derivative
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dihydro-2H-Pyrano[2,3-B]-Pyridin-6-Yl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete analytical data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.