Description

4-Chloro-7-(Phenylsulfonyl)-7H-Pyrrolo-[2,3-D]Pyrimidine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors, due to its versatile functional groups. It is essential for research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of protein kinase inhibitors for cancer treatment.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production.

Basic Information

Product Name	4-Chloro-7-(Phenylsulfonyl)-7H-Pyrrolo-[2,3-D]Pyrimidine-6-Carboxylic Acid
CAS No.	1346447-16-2
Molecular Formula	C₁₇H₁₀ClN₃O₄S
Molecular Weight	387.79 g/mol
Synonyms	4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-7-(phenylsulfonyl)-; 4-Chloro-7-(benzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; CAS 1346447-16-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(Phenylsulfonyl)-7H-Pyrrolo-[2,3-D]Pyrimidine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.