Description

6-Iodo-3,4-Dihydro-2H-Pyrano[3,2-B]Pyridin-8-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyranopyridine heterocyclic structure with an iodine substituent. This compound is of significant value for medicinal chemistry research and development, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile heterocyclic scaffold.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis Building Block: The iodine moiety provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	6-Iodo-3,4-Dihydro-2H-Pyrano[3,2-B]Pyridin-8-Ol
CAS No.	1346447-05-9
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	6-Iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridin-8-ol; 8-Hydroxy-6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine; 6-Iodo-8-hydroxy-3,4-dihydro-2H-pyrano[3,2-b]pyridine; 1346447-05-9; Pyrano[3,2-b]pyridin-8-ol, 6-iodo-3,4-dihydro-2H-
EINECS	Contact for details

Quality Control

Our 6-Iodo-3,4-Dihydro-2H-Pyrano[3,2-B]Pyridin-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.