Description

(S)-4-Benzyl-3-Phenylpiperazin-2-One is a high-purity chiral piperazinone derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. This compound is essential for pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) focused on developing enantiomerically pure drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents.
• CNS Drug Research: Building block for potential antipsychotic, antidepressant, or anxiolytic drug candidates.
• Oncology Research: Used in the synthesis of targeted cancer therapy molecules and kinase inhibitors.
• Asymmetric Synthesis: Serves as a chiral auxiliary or scaffold in stereoselective chemical transformations.
• Medicinal Chemistry: Core structure for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and production of clinical trial materials.

Basic Information

Product Name	(S)-4-Benzyl-3-Phenylpiperazin-2-One
CAS No.	1346418-26-5
Molecular Formula	C17H18N2O
Molecular Weight	266.34 g/mol
Synonyms	(S)-4-Benzyl-3-phenylpiperazin-2-one; (3S)-4-Benzyl-3-phenyl-2-piperazinone; (S)-4-Benzyl-3-phenyl-2-piperazinone; (S)-4-Benzyl-3-phenylpiperazin-2-one; 4-Benzyl-3-phenyl-2-piperazinone, (S)-; (S)-4-Benzyl-3-phenyl-1,4-diazinan-2-one; (3S)-4-Benzyl-3-phenylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-3-Phenylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.