Description

4-Nitro-2H-Pyrazole-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized pyrazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile nitro-substituted scaffold for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactive pyrazole core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry to study enzyme inhibition and structure-activity relationships (SAR).
• Academic & Contract Research: A valuable reagent for methodological development and synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	4-Nitro-2H-Pyrazole-3-Carboxylic Acid Methyl Ester
CAS No.	1345513-95-2
Molecular Formula	C5H5N3O4
Molecular Weight	171.11 g/mol
Synonyms	Methyl 4-Nitro-1H-Pyrazole-3-Carboxylate; Methyl 4-Nitro-2H-Pyrazole-3-Carboxylate; 4-Nitro-1H-pyrazole-3-carboxylic acid methyl ester; 3-Carbomethoxy-4-nitropyrazole; 4-Nitro-3-pyrazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Nitro-2H-Pyrazole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.