Description

1-Bromo-2-Methoxy-3-Methyl-5-Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides strategic sites for further functionalization, making it a critical intermediate in the development of complex molecules. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating advanced organic materials, including liquid crystals and organic semiconductors.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments due to its nitro and bromo functional groups.
• Academic & Contract Research: A valuable reagent for methodological studies and the construction of molecular libraries in academic and CRO settings.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.

Basic Information

Product Name	1-Bromo-2-Methoxy-3-Methyl-5-Nitrobenzene
CAS No.	1345471-89-7
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	2-Bromo-6-Methoxy-3-Nitrotoluene; 3-Methyl-2-Methoxy-5-Nitrobromobenzene; 5-Nitro-2-Bromo-6-Methoxytoluene; 1-Bromo-2-methoxy-3-methyl-5-nitro-benzene; 2-Methoxy-3-methyl-5-nitro-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methoxy-3-Methyl-5-Nitrobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.