Description

6-Amino-3-Iodo-2-Methyl-Benzoic Acid is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an amino and an iodo substituent on the benzoic acid core, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Serves as a building block in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, dyes, and advanced polymers.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for biochemical and diagnostic research applications.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Product Name	6-Amino-3-Iodo-2-Methyl-Benzoic Acid
CAS No.	1345444-50-9
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	2-Methyl-6-amino-3-iodobenzoic acid; 3-Iodo-2-methyl-6-aminobenzoic acid; 6-Amino-3-iodo-2-methylbenzoic acid; Benzoic acid, 6-amino-3-iodo-2-methyl-; AI3-52031; ZINC000103074793; AKOS025310889; BCP31333
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Iodo-2-Methyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.