Description

8-Bromo-6-Fluoro-1,2-Dihydroquinolin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a halogenated quinolinone core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition or other biological pathways where halogenated quinolones are active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides that utilize fluorinated and brominated heterocyclic compounds for enhanced activity and selectivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials due to its fused aromatic system.
• Chemical Synthesis Reference Standard: Employed as a pure standard in analytical chemistry for method development and quality control in chemical production.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Product Name	8-Bromo-6-Fluoro-1,2-Dihydroquinolin-2-One
CAS No.	1343369-88-9
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	8-Bromo-6-fluoro-2H-quinolin-2-one; 6-Fluoro-8-bromo-1,2-dihydroquinolin-2-one; 8-Bromo-6-fluoro-2-oxo-1,2-dihydroquinoline; 2H-Quinolin-2-one, 8-bromo-6-fluoro-; 1343369-88-9; 8-Br-6-F-DHQO
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-6-Fluoro-1,2-Dihydroquinolin-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.