Description

1-(3-Bromophenyl)-3-Oxocyclobutane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane ring structure functionalized with bromophenyl and carboxylic acid groups. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile reactive sites.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides and fungicides with specific mode-of-action.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring new organic reactions and synthetic methodologies.

Basic Information

Item	Detail
Product Name	1-(3-Bromophenyl)-3-Oxocyclobutane-1-Carboxylic Acid
CAS No.	1342653-06-8
Molecular Formula	C11H9BrO3
Molecular Weight	269.09 g/mol
Synonyms	3-Oxocyclobutane-1-carboxylic acid, 1-(3-bromophenyl)-; 1-(3-Bromophenyl)-3-oxocyclobutanecarboxylic acid; 3-(3-Bromophenyl)-3-oxocyclobutanecarboxylic acid; (3-Bromophenyl)-3-oxocyclobutane-1-carboxylic acid; Cyclobutanecarboxylic acid, 1-(3-bromophenyl)-3-oxo-; CAS 1342653-06-8
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-3-Oxocyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.