Description

Ethyl 5-Fluoro-2-Methyl-3-Nitrobenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic combination of fluorine, nitro, and ester functional groups, enabling precise molecular construction for high-value target compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated aromatic motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates for oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D labs for constructing complex molecules, leveraging the nitro group for further functionalization and the ester for hydrolysis or transesterification.
• Dye & Pigment Intermediate: Acts as a precursor in the development of specialized fluorinated dyes and pigments, contributing to color fastness and unique optical properties.

Basic Information

Product Name	Ethyl 5-Fluoro-2-Methyl-3-Nitrobenzoate
CAS No.	1342359-36-7
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	Ethyl 5-Fluoro-2-Methyl-3-Nitrobenzoate; 5-Fluoro-2-Methyl-3-Nitrobenzoic Acid Ethyl Ester; Benzoic acid, 5-fluoro-2-methyl-3-nitro-, ethyl ester; 3-Nitro-5-fluoro-2-methylbenzoic acid ethyl ester; Ethyl 3-Nitro-5-fluoro-o-toluate; 1342359-36-7; Ethyl 5-fluoro-2-methyl-3-nitrobenzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Fluoro-2-Methyl-3-Nitrobenzoate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with stringent control over related substances and residual solvents. Certificates of Analysis (COA) detailing lot-specific results are provided with each shipment, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability and purity. For long-term storage, consider an inert atmosphere (e.g., nitrogen or argon).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.