Description

6-Fluoro-8-Methoxy-1,2-Dihydroquinolin-2-One is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic quinolinone structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique fluorinated and methoxylated scaffold.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug molecules, especially in oncology and central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Fluorinated Compound Research: Serves as a valuable substrate in fluorochemistry research due to the presence of a fluorine atom, which can alter pharmacokinetic properties.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents and herbicides.
• Material Science Research: Investigated as a precursor for functional organic materials, such as ligands for catalysts or components in organic electronics.

Basic Information

Product Name	6-Fluoro-8-Methoxy-1,2-Dihydroquinolin-2-One
CAS No.	1341996-40-4
Molecular Formula	C₁₀H₈FNO₂
Molecular Weight	193.17 g/mol
Synonyms	8-Methoxy-6-fluoro-1,2-dihydroquinolin-2-one; 6-Fluoro-8-methoxy-2H-quinolin-2-one; 2H-Quinolin-2-one, 6-fluoro-8-methoxy-; 6-Fluoro-8-methoxy-2-quinolinone; 6-Fluoro-8-methoxy-1,2-dihydro-2-quinolone; 1341996-40-4; 6-Fluoro-8-methoxy-2-oxo-1,2-dihydroquinoline
EINECS	Contact for details

Quality Control

Our 6-Fluoro-8-Methoxy-1,2-Dihydroquinolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.