Description

4-Fluoro-3-Methyl-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring fluorine, methyl, and nitro substituents on a benzoic acid core, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing advanced organic electronic materials used in displays and lighting technologies.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments, where the nitro and carboxylic acid groups facilitate chromophore development.
• Cross-Coupling Reactions: The carboxylic acid functionality allows for easy derivatization, making it suitable for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and custom synthesis projects in academic and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	4-Fluoro-3-Methyl-5-Nitrobenzoic Acid
CAS No.	1341764-57-5
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	5-Nitro-3-methyl-4-fluorobenzoic Acid; 4-Fluoro-3-methyl-5-nitrobenzoic Acid; Benzoic acid, 4-fluoro-3-methyl-5-nitro-; 3-Methyl-4-fluoro-5-nitrobenzoic Acid; 4-Fluoro-3-methyl-5-nitro-benzoic acid; 1341764-57-5; 4-Fluoro-3-methyl-5-nitro benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-Methyl-5-Nitrobenzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard grade meets high-purity research and development requirements, with specifications tailored to support cGMP and ISO standards for advanced intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.