Description

6-Bromo-8-Chloroquinolin-2(1H)-One is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinolinone structure makes it a critical intermediate for developing novel pharmaceutical compounds and functional materials. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antimicrobial agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinolinone core.
• Material Science: Serves as a building block for creating organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinolinone motifs into larger molecular architectures.
• Academic & R&D: A valuable reagent for medicinal chemistry research and exploring new synthetic pathways in university and corporate laboratories.

Basic Information

Product Name	6-Bromo-8-Chloroquinolin-2(1H)-One
CAS No.	1341717-31-4
Molecular Formula	C9H5BrClNO
Molecular Weight	258.50 g/mol
Synonyms	6-Bromo-8-chloro-1,2-dihydroquinolin-2-one; 6-Bromo-8-chloro-2-hydroxyquinoline; 8-Chloro-6-bromoquinolin-2(1H)-one; 2(1H)-Quinolinone, 6-bromo-8-chloro-; 6-Bromo-8-chloro-2-quinolinol; 6-Bromo-8-chloro-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Chloroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.