Description

S-tert-Butyl 3-Oxo-5-(Trifluoromethyl)-2,9-Diazaspiro[5.5]Undecane-9-Carboxylate (Wxfs0418) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its spirocyclic and trifluoromethyl motifs.
• Protease Inhibitor Development: The diazaspiro[5.5]undecane core is a privileged structure in the design of inhibitors for various enzymes, including kinases and proteases.
• Chemical Biology Probes: Employed in the synthesis of tool compounds and molecular probes for investigating biological pathways and target validation.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale synthesis under current Good Manufacturing Practice (cGMP) guidelines where required.

Basic Information

Product Name	S-tert-Butyl 3-Oxo-5-(Trifluoromethyl)-2,9-Diazaspiro[5.5]Undecane-9-Carboxylate (Wxfs0418)
CAS No.	1341192-02-6
Molecular Formula	C15H23F3N2O3
Molecular Weight	336.35 g/mol
Synonyms	tert-Butyl 3-oxo-5-(trifluoromethyl)-2,9-diazaspiro[5.5]undecane-9-carboxylate; 2,9-Diazaspiro[5.5]undecane-9-carboxylic acid, 3-oxo-5-(trifluoromethyl)-, 1,1-dimethylethyl ester, (2S)-; WXFS0418; (S)-tert-Butyl 3-oxo-5-(trifluoromethyl)-2,9-diazaspiro[5.5]undecane-9-carboxylate; 1341192-02-6; 9-Boc-3-oxo-5-(trifluoromethyl)-2,9-diazaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our S-tert-Butyl 3-Oxo-5-(Trifluoromethyl)-2,9-Diazaspiro[5.5]Undecane-9-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your research and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.