Description

2-Benzyl-4-Cyano-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is a sophisticated spirocyclic organic intermediate of significant interest in advanced pharmaceutical synthesis. Its complex molecular architecture, featuring a diaza-spiro[4.5]decane core, makes it a valuable building block for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the process development and scale-up stages for new active pharmaceutical ingredients requiring a rigid, three-dimensional spirocyclic framework.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Benzyl-4-Cyano-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester
CAS No.	1341038-86-5
Molecular Formula	C21H29N3O2
Molecular Weight	355.48 g/mol
Synonyms	tert-Butyl 2-benzyl-4-cyano-2,8-diazaspiro[4.5]decane-8-carboxylate; 2,8-Diaza-spiro[4.5]decane-8-carboxylic acid, 2-(phenylmethyl)-4-cyano-, 1,1-dimethylethyl ester; 2-Benzyl-4-cyano-2,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; 8-Boc-2-benzyl-4-cyano-2,8-diazaspiro[4.5]decane; 2-Benzyl-4-cyano-2,8-diazaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester.
EINECS	Contact for details

Quality Control

Our 2-Benzyl-4-Cyano-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.