Description

4-(tert-Butoxycarbonylamino)-3-Chlorobenzoic Acid CAS NO 1340354-00-8 is a high-purity, protected amino acid derivative featuring both a carboxylic acid and a Boc-protected amine group on a chlorinated benzene ring. This compound serves as a critical pharmaceutical intermediate and custom synthesis building block, enabling the precise construction of complex molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Peptide Mimetics & Conjugate Synthesis: Used to incorporate chlorinated aromatic and protected amino acid motifs into peptide backbones or drug conjugates.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Ligand & Catalyst Development: Useful for creating specialized ligands or organocatalysts in asymmetric synthesis.
• Material Science: Potential monomer or linker for constructing functionalized polymers or dendritic structures.

Basic Information

Product Name	4-(tert-Butoxycarbonylamino)-3-Chlorobenzoic Acid
CAS No.	1340354-00-8
Molecular Formula	C12H14ClNO4
Molecular Weight	271.70 g/mol
Synonyms	3-Chloro-4-[(tert-butoxycarbonyl)amino]benzoic Acid; 4-[(tert-Butoxycarbonyl)amino]-3-chlorobenzoic Acid; 4-(Boc-amino)-3-chlorobenzoic Acid; Boc-3-Cl-4-Abz-OH; N-Boc-3-chloro-4-aminobenzoic Acid; 3-Chloro-4-aminobenzoic Acid N-Boc Derivative; 4-(N-Boc-amino)-3-chlorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(tert-Butoxycarbonylamino)-3-Chlorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.