Description

2-Chloro-7,8-Difluoroquinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated and fluorinated structure makes it a critical intermediate for developing novel compounds with enhanced biological activity and material properties. This product is primarily targeted at research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate within their respective fields.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for developing new antibacterial, antiviral, and anticancer agents.
• Agrochemical Research: Used to construct novel fungicides, herbicides, and insecticides, leveraging the fluorine atoms for improved metabolic stability and membrane permeability.
• Material Science: Serves as a building block for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, due to the quinoline core's electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex quinoline scaffolds into target molecules.
• Fluorinated Compound Libraries: An important reagent for medicinal chemistry and drug discovery programs focused on generating fluorinated compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	2-Chloro-7,8-Difluoroquinoline
CAS No.	1339595-32-2
Molecular Formula	C9H4ClF2N
Molecular Weight	199.59 g/mol
Synonyms	7,8-Difluoro-2-chloroquinoline; 2-Chloro-7,8-difluoroquinoline; Quinoline, 2-chloro-7,8-difluoro-; 1339595-32-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-7,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming the product meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.