Description

2,2,2-Trifluoro-1-(Tetrahydro-2H-Pyran-3-Yl)Ethanamine is a high-value fluorinated amine building block with a unique heterocyclic scaffold. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its trifluoroethylamine moiety can significantly influence biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecules with enhanced properties.

Application

• Key pharmaceutical intermediate for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Building block for agrochemical research, used in the synthesis of novel herbicides, fungicides, and insecticides with improved efficacy.
• Versatile synthon in organofluorine chemistry, enabling the introduction of the trifluoroethylamine group into complex molecular architectures.
• Precursor for the synthesis of ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Intermediate in the production of specialty polymers and materials, where fluorine incorporation can alter surface properties and stability.
• Starting material for chemical biology probes and diagnostic agents, leveraging its fluorine atoms for potential use in imaging techniques.

Basic Information

Product Name	2,2,2-Trifluoro-1-(Tetrahydro-2H-Pyran-3-Yl)Ethanamine
CAS No.	1339332-84-1
Molecular Formula	C7H12F3NO
Molecular Weight	183.17 g/mol
Synonyms	1-(Oxan-3-yl)-2,2,2-trifluoroethanamine; 3-(2,2,2-Trifluoroethylamino)tetrahydro-2H-pyran; 2,2,2-Trifluoro-1-(tetrahydro-2H-pyran-3-yl)ethan-1-amine; 2,2,2-Trifluoro-1-(3-tetrahydropyranyl)ethylamine; TF-THP-Ethanamine; 3-(Aminomethyl)-α,α,α-trifluoro-tetrahydro-2H-pyran; 2,2,2-Trifluoro-1-(3-pyranyl)ethylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Tetrahydro-2H-Pyran-3-Yl)Ethanamine is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.