Description

8-Oxa-2-Azaspiro[4.5]Decane-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemistry teams in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates to accelerate drug discovery and process development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel molecular libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Synthesis: Integral to the production route of Active Pharmaceutical Ingredients (APIs) that incorporate the 8-Oxa-2-azaspiro[4.5]decane moiety.
• Chemical Biology Probes: Serves as a building block for developing tool compounds and probes to study biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	8-Oxa-2-Azaspiro[4.5]Decane-4-Carboxylic Acid
CAS No.	1339071-65-6
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	8-Oxa-2-azaspiro[4.5]decane-4-carboxylic acid; 4-Carboxy-8-oxa-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decane-4-carboxylic acid, 8-oxa-; 8-Oxa-2-azaspiro[4.5]decan-4-carboxylic acid; Spiro[4.5]decane-4-carboxylic acid, 8-oxa-2-aza-; 1339071-65-6
EINECS	Contact for details

Quality Control

Our 8-Oxa-2-Azaspiro[4.5]Decane-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.