Description

8-Fluoro-4-Methoxyquinoline-2-Carboxylic Acid is a high-purity, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in antimicrobial and anticancer therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and fluorescent dyes due to the quinoline core.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	8-Fluoro-4-Methoxyquinoline-2-Carboxylic Acid
CAS No.	1338683-24-1
Molecular Formula	C₁₁H₈FNO₃
Molecular Weight	221.19 g/mol
Synonyms	8-Fluoro-4-methoxy-2-quinolinecarboxylic acid; 2-Quinolinecarboxylic acid, 8-fluoro-4-methoxy-; 8-Fluoro-4-methoxyquinoline-2-carboxylic acid; 1338683-24-1; 4-Methoxy-8-fluoroquinoline-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Methoxyquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.