Description

2-Hydroxy-6-Methyl-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its tetrahydroquinoline carboxylic acid core structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, offering precise chemical functionality for research and development. It is primarily utilized by pharmaceutical, agrochemical, and fine chemical manufacturers engaged in the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic architectures.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators that require the tetrahydroquinoline scaffold.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and pigments where its specific stereochemistry and functional groups are essential.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	2-Hydroxy-6-Methyl-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid
CAS No.	1338495-31-0
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	6-Methyl-1,2,3,4-tetrahydro-2-hydroxyquinoline-4-carboxylic acid; 4-Carboxy-6-methyl-1,2,3,4-tetrahydro-2-hydroxyquinoline; 2-Hydroxy-6-methyl-1,2,3,4-tetrahydro-4-quinolinecarboxylic acid; 6-Methyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (tautomer); THQ-4-COOH derivative; Light-sensitive tetrahydroquinoline acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methyl-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.