Description

4-[(4-Bromophenyl)Methyl]Oxane-4-Carboxylic Acid CAS NO 1338494-92-0 is a high-purity, advanced pharmaceutical intermediate featuring a unique oxane ring system substituted with a brominated aromatic moiety. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Building Block: Used to construct complex molecular architectures, leveraging the oxane scaffold and bromophenyl group for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides or fungicides where the bromine atom acts as a handle for further functionalization.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Academic and Institutional Research: Employed in universities and research institutes for exploratory organic synthesis and methodological studies.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for electronics or material science applications.

Basic Information

Product Name	4-[(4-Bromophenyl)Methyl]Oxane-4-Carboxylic Acid
CAS No.	1338494-92-0
Molecular Formula	C13H15BrO3
Molecular Weight	299.16 g/mol
Synonyms	4-[(4-Bromobenzyl)]tetrahydro-2H-pyran-4-carboxylic acid; 4-(4-Bromobenzyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(4-Bromophenylmethyl)tetrahydropyran-4-carboxylic acid; 4-(p-Bromobenzyl)tetrahydro-2H-pyran-4-carboxylic Acid; Oxane-4-carboxylic acid, 4-[(4-bromophenyl)methyl]-; THP-4-carboxylic acid, 4-(4-bromobenzyl)-; 1338494-92-0; 4-(4-Bromobenzyl)oxane-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-[(4-Bromophenyl)Methyl]Oxane-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.