Description

n-Boc-7-Azaspiro[3.5]Nonan-1-Ol is a protected amino alcohol derivative featuring a spirocyclic scaffold, which is a versatile and valuable building block in modern organic synthesis. This compound is critical for medicinal chemistry research, enabling the efficient construction of complex molecular architectures with potential biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the development of new drug candidates, particularly in the areas of central nervous system (CNS) and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Scaffold: Used to build and explore spirocyclic compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Research: Serves as a constrained, non-natural amino acid analog for designing peptide-like molecules with enhanced metabolic stability.
• Ligand and Probe Development: Employed in the creation of specialized chemical probes for biological target identification and validation.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective catalytic reactions.

Basic Information

Product Name	n-Boc-7-Azaspiro[3.5]Nonan-1-Ol
CAS No.	1338247-76-9
Molecular Formula	C13H23NO3
Molecular Weight	241.33 g/mol
Synonyms	1-Hydroxy-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; tert-Butyl 1-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate; 7-Boc-7-azaspiro[3.5]nonan-1-ol; 7-(tert-Butoxycarbonyl)-7-azaspiro[3.5]nonan-1-ol; 1-Hydroxy-7-azaspiro[3.5]nonane-7-carboxylic acid 1,1-dimethylethyl ester; 7-Azaspiro[3.5]nonan-1-ol, 7-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our n-Boc-7-Azaspiro[3.5]Nonan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.