Description

(S)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) where the (S)-piperidin-3-yl moiety is a core structural element.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in drug discovery and lead optimization programs.
• Asymmetric Synthesis: Employed in reactions requiring a chiral amine component to induce stereoselectivity in the final product.
• Process Development & Scale-up: Used in pilot plant and commercial manufacturing for developing robust, scalable synthetic routes.
• Contract Manufacturing (CMO): Supplied to Contract Manufacturing Organizations for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	(S)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride
CAS No.	1338222-39-1
Molecular Formula	C8H17N3O • HCl
Molecular Weight	207.70 g/mol
Synonyms	(S)-1-(3-Piperidinyl)-3,3-dimethylurea hydrochloride; (S)-3,3-Dimethyl-1-(3-piperidinyl)urea HCl; (S)-N-(Piperidin-3-yl)-N',N'-dimethylurea hydrochloride; Urea, N-(3-piperidinyl)-N',N'-dimethyl-, (S)-, hydrochloride; (S)-3,3-Dimethyl-1-(piperidin-3-yl)urea monohydrochloride; (S)-DMU-Pip HCl
EINECS	Contact for details

Quality Control

Our (S)-3,3-Dimethyl-1-(Piperidin-3-Yl)Ureahydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.