Description

6-(Benzyloxy)-3-Bromoquinoline is a high-purity brominated quinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its dual functionalization, offering versatile reactivity for constructing complex heterocyclic systems. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to introduce complex substituents.
• Ligand Synthesis: Utilized for preparing novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent probes or photoaffinity labels for biological target identification.

Basic Information

Product Name	6-(Benzyloxy)-3-Bromoquinoline
CAS No.	1337882-50-4
Molecular Formula	C₁₆H₁₂BrNO
Molecular Weight	314.18 g/mol
Synonyms	3-Bromo-6-(phenylmethoxy)quinoline; 3-Bromo-6-benzyloxyquinoline; Quinoline, 3-bromo-6-(phenylmethoxy)-; 6-Benzyloxy-3-bromoquinoline; 6-O-Benzyl-3-bromoquinoline
EINECS	Contact for details

Quality Control

Our 6-(Benzyloxy)-3-Bromoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply reliability and traceability meets the stringent demands of research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.