Description

1-Bromo-4-Chloro-2-Isopropoxybenzene is a high-purity, multi-functional halogenated aromatic ether building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a versatile building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogen and ether functionalities.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen substituents.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Buchwald-Hartwig amination to form biaryl and other complex structures.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	1-Bromo-4-Chloro-2-Isopropoxybenzene
CAS No.	1337606-32-2
Molecular Formula	C9H10BrClO
Molecular Weight	249.53 g/mol
Synonyms	4-Chloro-1-bromo-2-isopropoxybenzene; 2-Bromo-5-chloroanisole, isopropyl derivative; 2-Isopropoxy-4-chlorobromobenzene; 1-Bromo-4-chloro-2-(1-methylethoxy)benzene; 4-Chloro-2-isopropoxybromobenzene; 2-Bromo-5-chlorophenyl isopropyl ether; (2-Bromo-5-chlorophenoxy)propane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-2-Isopropoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.