Description

2-Trifluoromethyl-5,6,7,8-tetrahydro-quinolin-5-ylamine is a high-value, fluorinated heterocyclic amine building block of significant interest in advanced organic synthesis. This compound matters because its unique trifluoromethylated tetrahydroquinoline scaffold offers a powerful combination of lipophilicity, metabolic stability, and electronic properties sought after in modern chemical development. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study biological systems and enzyme functions.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) in fluorinated heterocycles.

Basic Information

Product Name	2-Trifluoromethyl-5,6,7,8-Tetrahydro-Quinolin-5-Ylamine
CAS No.	1337121-94-4
Molecular Formula	C10H11F3N2
Molecular Weight	216.20 g/mol
Synonyms	5-Amino-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline; 2-(Trifluoromethyl)-5,6,7,8-tetrahydroquinolin-5-amine; 5-Amino-2-trifluoromethyl-1,2,3,4-tetrahydroquinoline; 2-Trifluoromethyl-5,6,7,8-tetrahydroquinolin-5-amine; 5-Amino-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline; 2-Trifluoromethyl-5-amino-5,6,7,8-tetrahydroquinoline; 5,6,7,8-Tetrahydro-2-(trifluoromethyl)quinolin-5-amine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-5,6,7,8-tetrahydro-quinolin-5-ylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This amine compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.