Description

3-Bromo-5H-Cyclopenta[B]Pyridin-7(6H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its fused cyclopentapyridine core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in the construction of complex heterocyclic compounds for academic and industrial research.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Item	Detail
Product Name	3-Bromo-5H-Cyclopenta[B]Pyridin-7(6H)-One
CAS No.	1336955-89-5
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	3-Bromo-5H-cyclopenta[b]pyridin-7(6H)-one; 3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-7-one; 7(6H)-One, 3-bromo-5H-cyclopenta[b]pyridine; 3-Bromocyclopenta[b]pyridin-7(6H)-one
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5H-Cyclopenta[B]Pyridin-7(6H)-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with client specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.