Description

7-Bromo-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated and methoxylated tetrahydronaphthalenone structure. This compound is of significant value for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in constructing complex polycyclic frameworks due to its reactive ketone and halogen functional groups.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals, dyes, and advanced materials requiring specific brominated aromatic motifs.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	7-Bromo-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-One
CAS No.	1336953-53-7
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	7-Bromo-5-methoxy-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 7-bromo-5-methoxy-3,4-dihydro-; 7-Bromo-5-methoxy-α-tetralone; 5-Methoxy-7-bromo-α-tetralone; 7-Bromo-5-methoxy-1-tetralone; 7-Bromo-5-methoxytetral-1-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.