Description

n-(3S)-1-Azabicyclo[2.2.2]Oct-3-Yl-2,5-Dimethoxybenzamide Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the synthesis and development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and reliability for critical applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially in central nervous system (CNS) research.
• Neurological Research: Used as a reference standard or precursor in studies targeting nicotinic acetylcholine receptors and related neurological mechanisms.
• Process Development & Scale-up: Serves as a critical material for optimizing synthetic routes from laboratory to pilot and commercial scale production.
• Analytical Reference Standard: Provides a high-purity benchmark for method development, validation, and quality control testing in analytical laboratories.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities for therapeutic potential.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	n-(3S)-1-Azabicyclo[2.2.2]Oct-3-Yl-2,5-Dimethoxybenzamide Trifluoroacetate
CAS No.	1336913-03-1
Molecular Formula	C₁₈H₂₅F₃N₂O₅
Molecular Weight	406.40 g/mol
Synonyms	(3S)-1-Azabicyclo[2.2.2]oct-3-yl 2,5-dimethoxybenzamide trifluoroacetate; 2,5-Dimethoxy-N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]benzamide trifluoroacetate; (S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide TFA salt; Quinuclidine-3-yl benzamide derivative; TFA salt of n-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide
EINECS	Contact for details

Quality Control

Our n-(3S)-1-Azabicyclo[2.2.2]Oct-3-Yl-2,5-Dimethoxybenzamide Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent specifications suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.