Description

(3S)-1-Ethylpyrrolidin-3-Amine Dihydrochloride is a high-purity chiral amine building block and dihydrochloride salt of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for the development of novel pharmaceuticals, particularly in creating active pharmaceutical ingredients (APIs) with specific stereochemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for constructing complex molecules in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and other therapeutic agents.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the (3S)-1-ethylpyrrolidin-3-amine moiety into target molecules.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the design of novel bioactive compounds during drug discovery phases.
• Salt Formation Studies: The dihydrochloride form is studied for its influence on the physicochemical properties, stability, and bioavailability of drug candidates.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(3S)-1-Ethylpyrrolidin-3-Amine Dihydrochloride
CAS No.	1336912-66-3
Molecular Formula	C6H16N2·2HCl
Molecular Weight	197.12 g/mol
Synonyms	(3S)-1-Ethyl-3-pyrrolidinamine dihydrochloride; (S)-1-Ethylpyrrolidin-3-amine dihydrochloride; (S)-1-Ethyl-3-aminopyrrolidine dihydrochloride; 1-Ethyl-3(S)-aminopyrrolidine dihydrochloride; (3S)-1-Ethyl-3-aminopyrrolidine dihydrochloride; (S)-3-Amino-1-ethylpyrrolidine dihydrochloride; Pyrrolidine, 3-amino-1-ethyl-, (3S)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (3S)-1-Ethylpyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.